Gen 4:18 And unto Enoch was born Irad: and Irad begat Mehujael: and Mehujael begat Methusael: and Methusael begat Lamech.
Lamech means : conqueror, He was the seventh generation of Cain.
Gen 4:19 And Lamech took unto him two wives: the name of the one was Adah, and the name of the other Zillah.
Lamech was the first two have two wives, in opposition to God's command.
Gen 2:24 Therefore shall a man leave his father and his mother, and shall cleave unto his wife: and they shall be one flesh.
Adah means pleasure and Zillah means shade. Lamechs peeople prized outward beauty. This is the value of man, the appearance of things. God looks upon the heart.
1 Sam 16:7 But the LORD said unto Samuel, Look not on his countenance, or on the height of his stature; because I have refused him: for the LORD seeth not as man seeth; for man looketh on the outward appearance, but the LORD looketh on the heart.
The seventh generation of Seth, was Enoch who walked with God and God took him up.
Gen 4:20 And Adah bare Jabal: he was the father of such as dwell in tents, and of such as have cattle.
Gen 4:21 And his brother's name was Jubal: he was the father of all such as handle the harp and organ.
Satan was known for his musical abilities too.
Gen 4:22 And Zillah, she also bare Tubalcain, an instructor of every artificer in brass and iron: and the sister of Tubalcain was Naamah.
Probably, this is where the name Tuba, came from; a large brass musical instrument.
Gen 4:23 And Lamech said unto his wives, Adah and Zillah, Hear my voice; ye wives of Lamech, hearken unto my speech: for I have slain a man to my wounding, and a young man to my hurt.
Gen 4:24 If Cain shall be avenged sevenfold, truly Lamech seventy and sevenfold.
Lamech boasted in his killing, that and his beautiful wives , crafted things, music, and the city named after him. He was the model of the natural man, but all would be erased by the flood.
Gen 4:25 And Adam knew his wife again; and she bare a son, and called his name Seth: For God, said she, hath appointed me another seed instead of Abel, whom Cain slew.
Seth : hath appointed. (a replacement for Abel)
Gen 4:26 And to Seth, to him also there was born a son; and he called his name Enos: then began men to call upon the name of the LORD.
The lineage of Seth began to call upon the name of the LORD.